Description
Overview
Selank is a synthetic heptapeptide anxiolytic developed at the Institute of Molecular Genetics of the Russian Academy of Sciences — a stabilised analogue of the endogenous immunomodulatory tetrapeptide tuftsin, extended with the tripeptide Pro-Gly-Pro to significantly increase metabolic stability and duration of action. Approved as a drug in Russia since 2009 for generalised anxiety disorder, Selank is remarkable for producing meaningful anxiolytic effects through mechanisms entirely distinct from benzodiazepines or SSRIs — without sedation, cognitive blunting, or dependency risk.
What makes Selank exceptional in its class is its procognitive profile: unlike virtually every other anxiolytic compound, Selank appears to preserve or improve cognitive performance rather than impairing it. This makes it one of the most useful compounds for studying anxiety-cognition interactions in research settings.
Mechanism of Action
Selank’s anxiolytic profile arises from multi-target modulation of the brain’s primary inhibitory and modulatory systems. It potentiates GABAergic neurotransmission — the mechanism shared by benzodiazepines — through an indirect, modulatory pathway rather than direct receptor binding, which is why it lacks the tolerance, sedation, and withdrawal properties of classical GABAergic drugs.
Selank also inhibits enkephalin-degrading enzymes, extending the half-life of endogenous enkephalins and producing opioid-receptor-mediated mood stabilisation without direct opioid receptor binding. Additionally, it modulates IL-6 expression and the balance of T-helper cell populations, acting as an immunomodulator in stress-related immune dysregulation. Its documented effects on serotonin and dopamine systems show normalisation rather than artificial elevation of monoamine activity.
Key Research Applications
- ✓Anxiolytic without sedation — significantly reduces anxiety and tension markers without drowsiness or cognitive impairment
- ✓No dependency or withdrawal — modulates GABAergic system indirectly; no benzodiazepine-like tolerance development
- ✓Mood stabilisation — enkephalinase inhibition extends endogenous enkephalin action for sustained emotional regulation
- ✓Cognitive clarity under stress — unique among anxiolytics in preserving or improving cognitive performance simultaneously
- ✓Immunomodulatory — regulates IL-6 and T-cell balance; studied for stress-induced immune dysregulation
- ✓Memory consolidation — improves retention and recall, particularly under conditions of psychological stress
- ✓Anti-fatigue — reduces subjective and objective markers of mental fatigue in prolonged cognitive task research
- ✓Synergises with nootropics — anxiety reduction enables cleaner cognitive enhancement from complementary compounds
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Research Disclaimer: For research purposes only. Not for human consumption. Must be handled by qualified researchers in a laboratory setting.



Aaron T. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Amanda B. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Mike C. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Holly K. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Sean R. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
James A. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Rebecca M. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Ashley S. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Vanessa P. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Josh G. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Scott E. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
David T. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Gregory J. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Heather K. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Katelyn H. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Christina S. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Melissa D. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Kayla H. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Tyler J. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Kevin R. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Jerry J. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Katelyn B. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Sandra M. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Kayla P. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Mark N. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
James N. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Monica M. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Amanda H. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Patricia S. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Nathan N. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Patricia K. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Jerry R. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Aaron L. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Dennis G. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Jeffrey G. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Emily W. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Raymond L. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Adam E. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Justin L. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Holly D. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Jessica D. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Brittany H. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Jennifer W. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Christina D. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Ashley D. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Timothy E. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Kimberly P. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Sarah B. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Crystal K. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Andrew T. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Jeffrey A. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Mark A. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Michelle W. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Chris A. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Rebecca F. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Kyle N. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Ryan E. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Mike R. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Gregory C. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Danielle K. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Danielle S. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Megan F. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Nicole B. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Kimberly B. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Sandra W. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Sean J. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
David E. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Lauren S. (verified owner) –
Pretty impressed. was worried about quality but this is clearly a legit operation. will definitely be a repeat customer
Brian R. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Vanessa H. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Eric A. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Amber F. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Dennis N. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Emily F. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Rachel P. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Scott T. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Brandon C. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Michelle M. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Sarah P. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Kyle G. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Steven J. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
NeuropathR (verified owner) –
solid quality selank. dissolves perfectly, behaves as expected. would rate 5 stars but im just naturally cautious with new sources – about to reorder for the third time which says everything
AnxR lab (verified owner) –
selank is remarkable for what it does to anxiety markers without the sedation or tolerance issues of classical compounds. this source is clean – COA verified independently and matched perfectly
Stephanie M. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Frank L. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Jennifer F. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Samantha W. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
ResearchDr T (verified owner) –
the immunomodulatory aspect of selank is underappreciated. seeing interesting results in stress-induced immune dysregulation studies. quality from this source is consistently excellent
CogPeace R (verified owner) –
3rd order. still the best anxiolytic peptide I research. completely discreet packaging every time, fast shipping. the fact that cognitive performance doesnt drop under this protocol is the key differentiator
Daniel C. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Patrick G. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Frank T. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Raymond E. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use
Brian C. (verified owner) –
My doctor doesnt know about this lol but seriously the results speak for themselves. been using 6 weeks and feel great
Tiffany H. (verified owner) –
results took about 4 weeks to really feel but now I definitely notice when i miss a dose
Monica F. (verified owner) –
Good stuff all around. body composition slowly shifting in the right direction. will keep ordering
Chris G. (verified owner) –
this plus better sleep has been a game changer for my mental health. highly recommend to anyone struggling with focus
Timothy L. (verified owner) –
honestly shocked at how well this works. hunger cravings down significantly after just 2 weeks of use