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TB-500 10mg

TB-500 10mg

(146 customer reviews)

$64.99

25 in stock

SKU: bt10 Category:

Description

Overview

TB-500, the synthetic analogue of Thymosin Beta-4 (Tb4), is a 43-amino-acid peptide naturally present in virtually all nucleated cells. First isolated from bovine thymic tissue in the 1960s, Thymosin Beta-4 plays a fundamental role in actin sequestration — the dynamic regulation of the cellular cytoskeleton — which underlies its profound influence on cell migration, differentiation, and proliferation across every major tissue type in the body.

Unlike most healing peptides that act locally at an injection site, TB-500 circulates systemically via the bloodstream, making it uniquely effective for diffuse, multi-site, or systemic injury. Research models consistently demonstrate faster repair timelines, reduced fibrosis, and improved final tissue quality compared to untreated controls — across tendons, muscles, bone, cardiac tissue, and neurological structures.

Mechanism of Action

TB-500’s primary molecular action is the sequestration of G-actin monomers via its LKKTETQ domain, preventing premature actin polymerisation and maintaining a pool of free actin available for rapid cell motility. This enables swift migration of endothelial cells, keratinocytes, and immune cells to sites of injury — the foundational first step in any effective healing cascade.

TB-500 also upregulates metalloproteinase expression for extracellular matrix remodelling, promotes angiogenesis via VEGF signalling pathways, and suppresses NF-kB-mediated inflammation systemically. Its ability to modulate collagen I to collagen III ratios — reducing scar tissue formation — is particularly valuable in tendon and cardiac repair models where fibrosis limits functional recovery.

Key Research Applications

  • ✓Systemic tissue repair — acts throughout the body via bloodstream distribution rather than only at injection site
  • ✓Muscle fibre repair — activates satellite cells and promotes myoblast differentiation after injury or ischaemia
  • ✓Tendon & ligament healing — enhances fibroblast migration and collagen I/III remodelling for organised, strong repair
  • ✓Angiogenesis — stimulates new capillary formation via VEGF pathway to restore perfusion in damaged tissue
  • ✓Scar tissue reduction — modulates collagen deposition to reduce fibrosis and promote functional healing over scarring
  • ✓Cardiac repair — studied for cardiomyocyte regeneration after experimental myocardial infarction
  • ✓Neurological repair — promotes axonal sprouting and neurological recovery in spinal cord injury models
  • ✓Anti-inflammatory — downregulates NF-kB and pro-inflammatory cytokine cascades at the systemic level
Specifications
Peptide Thymosin Beta-4 Analogue
Active Sequence LKKTETQ (actin-binding domain)
Molecular Weight 4,963.5 Da
Purity ≥98% by HPLC
Vial Content 10mg lyophilised powder
Storage Keep refrigerated; 24-month shelf life lyophilised
Reconstitution Bacteriostatic water recommended
CoA Third-party certificate included with every order

Verified Quality & Discreet Shipping

Made in USAQuality GuaranteeShopper ApprovedNorton SecuredMcAfee Secure
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✓ Same-day dispatch on orders before 2pm
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✓ Fast tracked shipping 2-4 days
✓ Made in USA — GMP-compliant facility

Research Disclaimer: For research purposes only. Not for human consumption. Must be handled by qualified researchers in a laboratory setting.

146 reviews for TB-500 10mg

  1. Sarah H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  2. Ashley D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  3. Christina K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  4. David E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  5. Mark G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  6. Kayla B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  7. Nathan G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  8. Kayla H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  9. Josh A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  10. Brandon R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  11. Stephanie W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  12. Steven J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  13. Kimberly B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  14. Brian C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  15. Rebecca W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  16. Kevin C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  17. Crystal K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  18. Michelle F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  19. Timothy E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  20. Sean J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  21. Frank E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  22. Adam E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  23. Jennifer M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  24. Brittany B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  25. Katelyn P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  26. Crystal S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  27. Kevin J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  28. Rachel B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  29. Amber W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  30. Crystal D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  31. Jerry R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  32. Steven C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  33. Heather D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  34. Kimberly H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  35. Tiffany H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  36. Eric G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  37. Scott E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  38. Danielle K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  39. Amber F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  40. Brittany P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  41. Andrew L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  42. Andrew T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  43. Amanda H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  44. Monica W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  45. Scott L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  46. Raymond T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  47. Danielle S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  48. Patrick A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  49. Dennis N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  50. Sandra W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  51. Patricia D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  52. Tiffany B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  53. Nicole H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  54. Josh N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  55. Vanessa P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  56. Rachel H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  57. Mike C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  58. Lauren K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  59. Frank T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  60. James G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  61. Sandra F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  62. Brandon C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  63. Katelyn H. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  64. Justin E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  65. Heather S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  66. Patrick G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  67. Danielle D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  68. Michelle M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  69. Sarah B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  70. Jennifer F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  71. Nicole B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  72. Rebecca F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  73. Jeffrey G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  74. Tiffany P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  75. David L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  76. Mark N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  77. Rebecca M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  78. Chris G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  79. Kimberly P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  80. Timothy T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  81. Lauren D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  82. Jeffrey N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  83. Holly S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  84. Tyler R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  85. Michelle W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  86. Megan M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  87. Ashley K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  88. Patricia S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  89. Melissa K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  90. Adam L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  91. Gregory R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  92. Gregory J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  93. Adam T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  94. Monica M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  95. Kyle G. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  96. Samantha W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  97. Samantha M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  98. Megan W. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  99. James A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  100. Aaron T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  101. Patrick N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  102. Christina D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  103. Amanda P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  104. Sean C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  105. Andrew E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  106. Kyle N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  107. Samantha F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  108. Ryan T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  109. Tyler C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  110. Stephanie F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  111. Brian J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  112. Brandon J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  113. Jerry C. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  114. Sean R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  115. Daniel R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  116. Ryan L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  117. Justin T. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  118. Melissa S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  119. Timothy L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  120. Chris N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  121. Vanessa B. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  122. Steven R. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  123. Nicole P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  124. TrackCoach K (verified owner) –

    systemic effects are what makes this one stand out. working with multiple concurrent areas of concern in the research and this has been the most efficient option tried. will reorder

  125. Jessica S. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  126. Amber M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  127. Mike J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  128. Eric A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  129. Raymond L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  130. Kayla P. (verified owner) –

    Great product. been using alongside physical therapy and my PT even commented on how fast im healing. happy customer

  131. Emily M. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  132. Eric N. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  133. Dennis A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  134. Holly K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  135. Mike T (verified owner) –

    stacked this with BPC and the synergy is real, like genuinely noticeable difference vs either alone. old shoulder injury protocol from 2019 has been responding well over the last 2 months. the real deal

  136. Daniel J. (verified owner) –

    Completely changed how i approach weight management. this combined with intermittent fasting has been incredible

  137. Jessica K. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  138. Melissa D. (verified owner) –

    took longer to feel effects than i expected but around week 4 things started to improve. will continue using

  139. Kyle A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  140. Aaron L. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  141. Emily F. (verified owner) –

    longevity focused here and this fits perfectly into my protocol. effects really do build over time

  142. Mark A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  143. Aaron E. (verified owner) –

    Been using for cognitive support and the mental clarity improvement is real. focus during work is dramatically better

  144. John R Labs (verified owner) –

    really solid purity based on the COA. reconstituted smoothly, no cloudiness or particulate. 6 weeks into the research and seeing exactly what the literature predicts

  145. Nathan A. (verified owner) –

    Five stars no question. this has helped my gut issues more than anything else ive tried and i tried A LOT of things over the years

  146. peptide nerd (verified owner) –

    good product, fast ship. wish there was a loyalty discount for repeat orders but the quality justifies the price. been through 3 vials with consistent results each time

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